The concept of medical tourism is not a new one. The first recorded instance of medical tourism dates back to thousands of years when Greek pilgrims journeyed from across the Mediterranean to Epidauria, a small area in the Saronic Gulf, where the healing god Asklepios dwelled in his sanctuary. Thus, Epidauria became the birthplace of medical tourism. Today, medical tourism is a concept becoming more of a mercurial issue in globalisation. Without equivocation, medical tourism ensures that people in need of treatment, though living in different parts of the world, do not only have to consider medical options in their respective countries, but may also choose treatment in various other countries that have advanced technology, reasonable prices, and high standards. Every year, millions of people all over the world travel for diagnoses, treatment, and operations in general surgery, eye diseases, oncology, cardiology, and in many other areas of medicine. Moreover, the primary reasons for such travel are several: the treatment costs are less expensive than those in their own countries; the technologies used are more advanced; and higher quality healthcare personnel are accessible with shorter waiting periods for patients. The type of transportation, the provision of suitable accommodations, the communication between the patient and the healthcare center, and adapting to the conditions of the country where they arrive – these are among the leading issues patients and their relatives most often face during these travels. Formerly, Istanbul promoted the city for tourism and trade, whose prominent history, cosmopolitan atmosphere, and differing cultural backgrounds bridged Europe and Asia – one of the most vital cities in the world for centuries. Today Istanbul has advanced a step further as one of the most important destinations in medical tourism, not just a city for tourism and trade. Istanbul’s main advantages in medical tourism include less flight time than to other medical tourism destinations such as Thailand, Singapore, or India; fully equipped and high standard healthcare centres; state-of-the art technology such as CyberKnife, Rapid Arc, and more; the most renown doctors in the world; and fast, easy visa procedures. Medical City acts as a bridge between patients and their treatment to eliminate all these problems.